What is the meaning of
Nam-Myoho-Renge-Kyo? 
 

Myoho-Renge-Kyo is the ultimate Law or true entity of life permeating the universe. It also signifies the name of the True Buddha as Myoho-Renge-Kyo is the same and identical with the life of the true Buddha from the beginningless past. Another interpretation of Myoho-Renge-Kyo is the essence and the heart of all sutras, and the most supreme and correct Law.

The meaning of each of the words is infinitely profound and goes beyond a literal definition. "Nam"originally derives from ancient Sanskrit.  The closest translation of "Nam" is "devotion of our mind and body." Next, "Myoho-Renge" signifies the ultimate reality of the universe to which the Original Buddha, Nichiren Daishonin is enlightened, and "Kyo" inidicates the expressed teaching of the significance of "Myoho-Renge."

 
 
 
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In Nichiren Daishonin’s Gosho, “Reply to the Wife of Lord Ueno”
(“Ueno ama gozen-gohenji”) it states the following:

”The Lotus Sutra teaches that the hands used to hold it will immediately enter Buddhahood, and the mouth that chants the Daimoku will instantly become a Buddha.... The Lotus Sutra states, ‘Among those who hear this Law, there is not one who shall not attain enlightenment.’ This passage means that if there are a hundred or even a thousand people who embrace this sutra, all will become Buddhas without exception.”
— (Gosho, p. 1574)